Bill C-55 Revisited

Cloning and consensus: Bill C-6.

C&L Intention Revisited

The 1990 papers of Cohen and Levesque (C&L) on rational interaction have been most influential. Their approach is based on a logical framework integrating the concepts of belief, action, time, and choice. On top of these they define notions of achievement goal, persistent goal, and intention. We here revisit their approach in a simplified, propositional logic, for which we give complete axiomat...

Vitamin C revisited

This narrative review summarizes the role of vitamin C in mitigating oxidative injury-induced microcirculatory impairment and associated organ failure in ischemia/reperfusion or sepsis. Preclinical studies show that high-dose vitamin C can prevent or restore microcirculatory flow impairment by inhibiting activation of nicotinamide adenine dinucleotide phosphate-oxidase and inducible nitric oxid...

Bill C-442: Shining the limelight on the Lyme-like?

1Department of Medicine, Royal Inland Hospital, Kamloops, British Columbia; 2Departments of Medicine, Critical Care Medicine, Pathology and Laboratory Medicine, and Community Health Sciences, University of Calgary, Calgary, Alberta; 3Department of Microbiology-Infectious Diseases, Université de Sherbrooke, Sherbrooke, Quebec Correspondence: Dr Kevin B Laupland, Royal Inland Hospital, 311 Columb...

Vitamin C and cancer revisited.

I n this issue of PNAS, Chen et al. (1) show that i.p. injection of ‘‘pharmacologic doses’’ of vitamin C decreases the growth and weight of human, rat, and murine tumor xenografts in athymic, nude mice. This work follows a number of articles by the same group, led by Mark Levine at the National Institute of Diabetes and Digestive and Kidney Diseases, showing that millimolar concentrations of ex...